Maleylacetate reductase explained

maleylacetate reductase
Ec Number:1.3.1.32
Cas Number:69669-65-4
Go Code:0018506

In enzymology, a maleylacetate reductase is an enzyme that catalyzes the chemical reaction

3-oxoadipate + NAD(P)+

\rightleftharpoons

2-maleylacetate + NAD(P)H + H+

The 3 substrates of this enzyme are 3-oxoadipate, NAD+, and NADP+, whereas its 4 products are 2-maleylacetate, NADH, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3-oxoadipate:NAD(P)+ oxidoreductase. This enzyme is also called maleolylacetate reductase. This enzyme participates in 3 metabolic pathways: gamma-hexachlorocyclohexane degradation, benzoate degradation via hydroxylation, and 1,4-dichlorobenzene degradation.

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