Magnesium protoporphyrin IX methyltransferase explained
| magnesium protoporphyrin IX methyltransferase |
| Ec Number: | 2.1.1.11 |
| Cas Number: | 9029-82-7 |
| Go Code: | 0046406 |
| Width: | 270 |
In enzymology, a magnesium protoporphyrin IX methyltransferase is an enzyme that catalyzes the chemical reaction
S-adenosyl-L-methionine + magnesium protoporphyrin IX
S-adenosyl-L-homocysteine + magnesium protoporphyrin IX 13-methyl ester
The two substrates of this enzyme are S-adenosyl methionine and magnesium protoporphyrin IX; its two products are S-adenosylhomocysteine and magnesium protoporphyrin IX 13-methyl ester.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:magnesium-protoporphyrin-IX O-methyltransferase. This enzyme is part of the biosynthetic pathway to chlorophylls.[1] [2]
See also
References
- GIBSON KD, NEUBERGER A, TAIT GH . 1963 . STUDIES ON THE BIOSYNTHESIS OF PORPHYRIN AND BACTERIOCHLOROPHYLL BY RHODOPSEUDOMONAS SPHEROIDES. 4. S-ADENOSYLMETHIONINEMAGNESIUM PROTOPORPHYRIN METHYLTRANSFERASE . Biochem. J. . 88 . 325 - 34 . 14063871 . 1202116 .
- Shepherd M, Reid JD, Hunter CN . 2003 . Purification and kinetic characterization of the magnesium protoporphyrin IX methyltransferase from Synechocystis PCC6803 . Biochem. J. . 371 . 351 - 60 . 12489983 . 10.1042/BJ20021394 . Pt 2 . 1223276 .
- Bollivar DW, Jiang ZY, Bauer CE, Beale SI . 1994 . Heterologous expression of the bchM gene product from Rhodobacter capsulatus and demonstration that it encodes S-adenosyl-L-methionine:Mg-protoporphyrin IX methyltransferase . J. Bacteriol. . 176 . 5290 - 6 . 8071204 . 17 . 196713 .
- Gibson LC, Hunter CN . 1994 . The bacteriochlorophyll biosynthesis gene, bchM, of Rhodobacter sphaeroides encodes S-adenosyl-L-methionine: Mg protoporphyrin IX methyltransferase . FEBS Lett. . 352 . 127 - 30 . 7925960 . 10.1016/0014-5793(94)00934-1 . 2 .
- Ebbon JG, Tait GH . 1969 . Studies on S-adenosylmethionine-magnesium protoporphyrin methyltransferase in Euglena gracilis strain Z . Biochem. J. . 111 . 573 - 82 . 5774480 . 4 . 1187578 .
Notes and References
- Biosynthesis of chlorophylls from protoporphyrin IX . Willows . Robert D. . Natural Product Reports . 2003 . 20 . 6 . 327–341 . 10.1039/B110549N . 12828371.
- 10.1007/s11120-006-9076-6 . Recent advances in chlorophyll biosynthesis . 2007 . Bollivar . David W. . Photosynthesis Research . 90 . 2 . 173–194 . 17370354 .
