Lysyltransferase Explained

lysyltransferase
Ec Number:	2.3.2.3
Cas Number:	37257-20-8
Go Code:	0050071

In enzymology, a lysyltransferase is an enzyme that catalyzes the chemical reaction

L-lysyl-tRNA + phosphatidylglycerol

\rightleftharpoons tRNA + 3-phosphatidyl-1'-(3'-O-L-lysyl)glycerol

Thus, the two substrates of this enzyme are L-lysyl-tRNA and phosphatidylglycerol, whereas its two products are tRNA and 3-phosphatidyl-1'-(3'-O-L-lysyl)glycerol.

This enzyme belongs to the family of transferases, specifically the aminoacyltransferases. The systematic name of this enzyme class is L-lysyl-tRNA:phosphatidylglycerol 3-O-lysyltransferase.

References

• Lennarz WJ, Bonsen PP, van Deenen LL . 1967 . Substrate specificity of O-L-lysylphosphatidylglycerol synthetase Enzymatic studies on the structure of O-L-lysylphosphatidylglycerol . Biochemistry . 6 . 2307 - 12 . 6049461 . 10.1021/bi00860a005 . 8 .