Lysine decarboxylase explained

Ec Number:4.1.1.18
Cas Number:9024-76-4
Go Code:0008923

The enzyme Lysine decarboxylase converts lysine to cadaverine.[1] [2]

Abbreviated as Ldc, the enzyme is involved in acid-stress response in Enterobacteria. The mode of action is the proton consumption, thereby reducing the overall acidity of its environnement.

Notes and References

  1. Gale EF, Epps HM . Studies on bacterial amino-acid decarboxylases: 1. l(+)-lysine decarboxylase . Biochem. J. . 38 . 3 . 232–42 . 1944 . 10.1042/bj0380232 . 16747785 . 1258073 .
  2. Soda K, Moriguchi M . Crystalline lysine decarboxylase . Biochem. Biophys. Res. Commun. . 34 . 1 . 34–9 . January 1969 . 5762458 . 10.1016/0006-291X(69)90524-5.