Lophine Explained

Lophine is the organic compound with the formula . It is a derivative of imidazole wherein all three carbon atoms have phenyl groups as substituents. A white solid, this compound gave the first example of chemiluminescence when its basic solutions were exposed to air.[1] Its chemiluminescence continues to attract attention.[2]

Lophine is prepared by condensation of benzaldehyde, benzil, and ammonia.[3]

References

  1. 10.1002/cber.18770100122 . Untersuchungen über Hydrobenzamid, Amarin und Lophin . 1877 . Radziszewski . B. R. . Berichte der Deutschen Chemischen Gesellschaft . 10 . 70–75 .
  2. 10.1002/bmc.226 . Lophine derivatives as versatile analytical tools . 2003 . Nakashima . Kenichiro . Biomedical Chromatography . 17 . 2–3 . 83–95 . 12717796 .
  3. 10.1002/jhet.4771 . Catalyst-free one-pot synthesis of 2,4,5-tri- and 1,2,4,5-tetrasubstituted imidazoles . 2024 . Bandivadekar . Priyanka V. . Chaturbhuj . Ganesh U. . Journal of Heterocyclic Chemistry . 61 . 3 . 430–438 .

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