Lipoyl amidotransferase explained

Lipoyl amidotransferase
Ec Number:	2.3.1.200

Lipoyl amidotransferase (LipL (gene)) is an enzyme with systematic name (glycine cleavage system H)-N⁶-lipoyl-L-lysine:(lipoyl-carrier protein)-N⁶-L-lysine lipoyltransferase.^[1] This enzyme catalyses the following chemical reaction

[glycine cleavage system H]-N⁶-lipoyl-L-lysine + [lipoyl-carrier protein]

\rightleftharpoons glycine cleavage system H + [lipoyl-carrier protein]-N⁶-lipoyl-L-lysine

In the bacterium Listeria monocytogenes the enzyme takes part in a pathway for scavenging of lipoic acid.

Notes and References

1. Christensen QH, Hagar JA, O'Riordan MX, Cronan JE . A complex lipoate utilization pathway in Listeria monocytogenes . The Journal of Biological Chemistry . 286 . 36 . 31447–56 . September 2011 . 21768091 . 3173067 . 10.1074/jbc.m111.273607 . free .