Leucogenenol Explained

Leucogenenol is a blood cell stimulating secondary metabolite isolated from the mold Penicillium gilmanii. Its chemical structure was reported;^[1] however, later studies determined that the original structure is incorrect and the true chemical structure of leucogenenol remains unknown.^{[2] [3]}

Notes and References

1. Structure of leucogenenol . Rice, F. A. H. . Journal of the Chemical Society C: Organic . 1971 . 15 . 2599–606. 10.1039/j39710002599 . 5167554 .
2. 10.1021/ja00368a015 . Salomon, Robert G. . Salomon, Mary F. . Zagorski, Michael G. . Reuter, James M. . Coughlin, Daniel J. . Total synthesis refutes the postulated structure of leucogenenol . Journal of the American Chemical Society . 1982 . 104 . 4 . 1008–13.
3. 10.1021/jo00187a026 . Synthesis of 3-hydroxy-3-(hydroxymethyl)-5-methylcyclohexane-1,2-dione dibenzoate, a reported hydrolytic degradation product of leucogenenol . Aberhart, D. John . Clardy, Jon . Ghoshal, Pallab K. . Cunheng, He . Zheng, Qitai . Journal of Organic Chemistry . 1984 . 49 . 13 . 2429–33.