Leucine carboxyl methyltransferase 1 explained

Leucine carboxyl methyltransferase 1 is an enzyme that in humans is encoded by the LCMT1 gene.^{[1] [2]}

Interactions

LCMT1 has been shown to interact with FXR2.^[3]

Further reading

• Lee JA, Pallas DC . Leucine carboxyl methyltransferase-1 is necessary for normal progression through mitosis in mammalian cells . The Journal of Biological Chemistry . 282 . 42 . 30974–84 . Oct 2007 . 17724024 . 3516869 . 10.1074/jbc.M704861200 . free .
• De Baere I, Derua R, Janssens V, Van Hoof C, Waelkens E, Merlevede W, Goris J . Purification of porcine brain protein phosphatase 2A leucine carboxyl methyltransferase and cloning of the human homologue . Biochemistry . 38 . 50 . 16539–47 . Dec 1999 . 10600115 . 10.1021/bi991646a .
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S . Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library . Gene . 200 . 1–2 . 149–56 . Oct 1997 . 9373149 . 10.1016/S0378-1119(97)00411-3 .
• Maruyama K, Sugano S . Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides . Gene . 138 . 1–2 . 171–4 . Jan 1994 . 8125298 . 10.1016/0378-1119(94)90802-8 .

Notes and References

1. Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W . Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics . Genome Research . 10 . 5 . 703–13 . May 2000 . 10810093 . 310876 . 10.1101/gr.10.5.703 .
2. Web site: Entrez Gene: LCMT1 leucine carboxyl methyltransferase 1.
3. Huda Zoghbi . Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M . Towards a proteome-scale map of the human protein-protein interaction network . Nature . 437 . 7062 . 1173–8 . Oct 2005 . 16189514 . 10.1038/nature04209 . 2005Natur.437.1173R . 4427026 .