| lactate—malate transhydrogenase | |
| Ec Number: | 1.1.99.7 |
| Cas Number: | 9077-15-0 |
| Go Code: | 0050042 |
In enzymology, a lactate—malate transhydrogenase is an enzyme that catalyzes the chemical reaction
(S)-lactate + oxaloacetate
\rightleftharpoons
Thus, the two substrates of this enzyme are (S)-lactate and oxaloacetate, whereas its two products are pyruvate and malate.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is (S)-lactate:oxaloacetate oxidoreductase. This enzyme is also called malate-lactate transhydrogenase. This enzyme participates in pyruvate metabolism. It employs one cofactor, nicotinamide D-ribonucleotide.