| lactaldehyde reductase | |
| Ec Number: | 1.1.1.77 |
| Cas Number: | 37250-15-0 |
| Go Code: | 0008912 |
In enzymology, a lactaldehyde reductase is an enzyme that catalyzes the chemical reaction
(R)[or (S)]-propane-1,2-diol + NAD+
\rightleftharpoons
The 3 substrates of this enzyme are (R)-propane-1,2-diol, (S)-propane-1,2-diol, and NAD+, whereas its 4 products are (R)-lactaldehyde, (S)-lactaldehyde, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (R)[or (S)]-propane-1,2-diol:NAD+ oxidoreductase. Other names in common use include propanediol:nicotinamide adenine dinucleotide (NAD+) oxidoreductase, and L-lactaldehyde:propanediol oxidoreductase. This enzyme participates in pyruvate metabolism and glyoxylate and dicarboxylate metabolism.
As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes,, and .