Keratosis follicularis spinulosa decalvans explained
Keratosis follicularis spinulosa decalvans is a rare X-linked disorder described by Siemens in 1926. It is a disease that begins in infancy with keratosis pilaris localized on the face, then evolves to more diffuse involvement.[1] [2] [3]
An association with SAT1 has been suggested.[4]
See also
Notes and References
- James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. .
- Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. .
- Book: Rapini, Ronald P. . Bolognia, Jean L. . Jorizzo, Joseph L. . Dermatology: 2-Volume Set . Mosby . St. Louis . 2007 . 978-1-4160-2999-1 .
- Gimelli . G. . Giglio . S. . Zuffardi . O. . Alhonen . L. . Suppola . S. . Cusano . R. . Lo Nigro . C. . Gatti . R. . Ravazzolo . R. . Seri . Marco . Gene dosage of the spermidine/spermine N(1)-acetyltransferase (SSAT) gene with putrescine accumulation in a patient with a Xp21.1p22.12 duplication and keratosis follicularis spinulosa decalvans (KFSD) . Hum Genet . 111 . 3 . 235–41 . Sep 2002 . 10.1007/s00439-002-0791-6 . 12215835 . 23842885 . 8 .