Juncusol Explained

Juncusol is a 9,10-dihydrophrenathrene found in Juncus species such as J. acutus,^[1] J. effusus^{[2] [3]} or J. roemerianus.^{[4] [5]}

It can also be synthesized.^{[6] [7] [8]}

This compound shows antimicrobial activity against Bacillus subtilis and Staphylococcus aureus.^[4] It also has a toxic effect on estuarine fish and shrimp.^[9]

External links

• Juncusol at kanaya.naist.jp/knapsack_jsp

Notes and References

1. 10.1248/cpb.55.1264. Phenanthrenoids from Juncus acutus L., New Natural Lipopolysaccharide-Inducible Nitric Oxide Synthase Inhibitors. Chemical & Pharmaceutical Bulletin. 55. 8. 1264. 2007. Behery. Fathi Abdelmohsen Abdelhalim. Naeem. Zain Elabdin Metwally. Maatooq. Galal Taha. Amer. Mohamed Mahmoud Abdelfattah. Wen. Zhi-Hong. Sheu. Jyh-Horng. Ahmed. Atallah Fouad. free.
2. Bhattacharyya . Experientia . 36 . 1980 . 27–28 . 10.1007/bf02003949 . Structure of effusol: A new phenolic constituent from Juncus effusus. 41731083 .
3. Shima . Phytochemistry . 30 . 1991 . 3149–3151 . 10.1016/s0031-9422(00)98276-1 . Phenanthrene derivatives from the medullae of Juncus effusus. 9 .
4. 10.1016/0024-3205(81)90609-3. 6796796. Antimicrobial activity of juncusol, a novel 9-10-dihydrophenanthrene from the marsh plant. Life Sciences. 29. 19. 1997–2001. 1981. Chapatwala. Kirit D.. de la Cruz. Armando A.. Miles. D.Howard.
5. 830696. 1977. Miles. D. H.. The structure of juncusol. A novel cytotoxic dihydrophenanthrene from the Estuarine marsh plant Juncus roemerianus. Journal of the American Chemical Society. 99. 2. 618–20. Bhattacharyya. J. Mody. N. V.. Atwood. J. L.. Black. S. Hedin. P. A.. 10.1021/ja00444a056.
6. 10.1016/S0040-4039(01)85715-4. Total synthesis of juncusol. Tetrahedron Letters. 19. 47. 4723. 1978. McDonald. Edward. Martin. Roger T..
7. 10.1021/jo00195a034. Regiospecific total synthesis of juncusol. The Journal of Organic Chemistry. 49. 21. 4045. 1984. Boger. Dale L.. Mullican. Michael D..
8. 10.1016/S0040-4039(00)79645-6. A novel synthesis of juncusol. Tetrahedron Letters. 32. 10. 1279. 1991. Jacobi. Peter A.. Zheng. Wanjun.
9. 7098770. 1982. de la Cruz. A. A.. Toxic effects of juncusol, a marsh plant phenolic extract, on estuarine fish and shrimp. Life Sciences. 30. 21. 1805–10. Miles. D. H.. Chapatwala. K. D.. 10.1016/0024-3205(82)90317-4.