Josamycin Explained
Josamycin is a macrolide antibiotic. It was isolated by Hamao Umezawa and his colleagues from strains of Streptomyces narbonensis var. josamyceticus var. nova in 1964.[1] [2]
It is currently sold in various countries.Brand examples are:
- Europe: Josalid, Josacine, Iosalide, Josamina
- Russia: Wilprafen (Вильпрафен)
- Japan: Josamy
Adverse effects
There has been a case report of edema of the feet.[3]
Notes and References
- Osono T, Oka Y, Watanabe S, Okami Y, Umezawa H . A new antibiotic, josamyicn. I. Isolation and physico-chemical characteristics . The Journal of Antibiotics . 20 . 3 . 174–180 . July 1967 . 6072798 .
- Umezawa H . Discovery of josamycin . Giornale Italiano di Chemioterapia . 29 . 1–10 . 1982 . Suppl 1 . 6765367 .
- Bosch X, Pedrol E, Casado X, Urbano-Marquez A . Josamycin-induced pedal oedema . BMJ . 307 . 6895 . 26 . July 1993 . 8343666 . 1678472 . 10.1136/bmj.307.6895.26-a .