Isoquinoline 1-oxidoreductase explained
| isoquinoline 1-oxidoreductase |
| Ec Number: | 1.3.99.16 |
| Cas Number: | 155948-73-5 |
| Go Code: | 0047121 |
In enzymology, an isoquinoline 1-oxidoreductase is an enzyme that catalyzes the chemical reaction
isoquinoline + acceptor + H2O
isoquinolin-1(2H)-one + reduced acceptor
The 3 substrates of this enzyme are isoquinoline, acceptor, and H2O, whereas its two products are isoquinolin-1(2H)-one and reduced acceptor.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with other acceptors. The systematic name of this enzyme class is isoquinoline:acceptor 1-oxidoreductase (hydroxylating).
References
- Lehmann M, Tshisuaka B, Fetzner S, Roger P, Lingens F . 1994 . Purification and characterization of isoquinoline 1-oxidoreductase from Pseudomonas diminuta 7, a novel molybdenum-containing hydroxylase . J. Biol. Chem. . 269 . 11254 - 60 . 8157655 . 15 .
- Lehmann M, Tshisuaka B, Fetzner S, Lingens F . 1995 . Molecular cloning of the isoquinoline 1-oxidoreductase genes from Pseudomonas diminuta 7, structural analysis of iorA and iorB, and sequence comparisons with other molybdenum-containing hydroxylases . J. Biol. Chem. . 270 . 14420 - 9 . 7782304 . 10.1074/jbc.270.24.14420 . 24 . free .
