Interferon-inducible GTPase explained

Symbol:IIGP
Interferon-inducible GTPase (IIGP)
Pfam:PF05049
Pfam Clan:CL0023
Interpro:IPR007743

In molecular biology, the interferon-inducible GTPase (IIGP) family of proteins is thought to play a role in intracellular defence. IIGP is predominantly associated with the Golgi apparatus and also localises to the endoplasmic reticulum and exerts a distinct role in IFN-induced intracellular membrane trafficking or processing.[1]

Members of this family include interferon-inducible GTPase 5 and immunity-related GTPase family M protein.

Notes and References

  1. Zerrahn J, Schaible UE, Brinkmann V, Guhlich U, Kaufmann SH . The IFN-inducible Golgi- and endoplasmic reticulum- associated 47-kDa GTPase IIGP is transiently expressed during listeriosis . J. Immunol. . 168 . 7 . 3428–36 . April 2002 . 11907101 . 10.4049/jimmunol.168.7.3428. free .

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Interferon-inducible GTPase".

Except where otherwise indicated, Everything.Explained.Today is © Copyright 2009-2024, A B Cryer, All Rights Reserved. Cookie policy.