Anterior cerebral artery explained

Anterior cerebral artery
Latin:arteria cerebri anterior
Branchfrom:Internal carotid artery
Vein:Cerebral veins
Supplies:Cerebrum

The anterior cerebral artery (ACA) is one of a pair of cerebral arteries that supplies oxygenated blood to most midline portions of the frontal lobes and superior medial parietal lobes of the brain. The two anterior cerebral arteries arise from the internal carotid artery and are part of the circle of Willis. The left and right anterior cerebral arteries are connected by the anterior communicating artery.

Anterior cerebral artery syndrome refers to symptoms that follow a stroke occurring in the area normally supplied by one of the arteries. It is characterized by weakness and sensory loss in the lower leg and foot opposite to the lesion and behavioral changes.

Structure

The anterior cerebral artery is divided into 5 segments. Its smaller branches: the callosal (supracallosal) arteries are considered to be the A4 and A5 segments.[1]

Development

The anterior cerebral artery develops from a primitive anterior division of the internal carotid artery that initially supplies the optic and olfactory regions. This anterior division, which appears at the twenty-eighth day of development, also forms the middle cerebral artery and the anterior choroidal artery. The anterior cerebral arteries grow toward each other and form the anterior communicating artery at the 21–24 mm stage of the embryo.[2]

Variation

The anterior cerebral artery shows considerable variation. In a study made using MRA, the most common variation was an underdeveloped A1 segment (5.6%), followed by the presence of an extra A2 segment (3%). In 2% of cases there was only one A2 segment.[3]

Function

The anterior cerebral artery supplies a part of the frontal lobe, specifically its medial surface and the upper border. It also supplies the front four–fifths of the corpus callosum, and provides blood to deep structures such as the anterior limb of the internal capsule, part of the caudate nucleus, and the anterior part of the globus pallidus.[4]

Clinical significance

Occlusion

See main article: Anterior cerebral artery syndrome. Strokes that occur in a part of the artery prior to the anterior communicating usually do not produce many symptoms because of collateral circulation. If a blockage occurs in the A2 segment or later, the following signs and symptoms may be noted:[5]

See also

External links

Notes and References

  1. Biller. J. 2007. Neurovascular System. Textbook of Clinical Neurology (Third Edition). Chapter 22. 405–434.
  2. Menshawi. K. Mohr. JP. Gutierrez. J. A Functional Perspective on the Embryology and Anatomy of the Cerebral Blood Supply.. Journal of Stroke. May 2015. 17. 2. 144–58. 10.5853/jos.2015.17.2.144. 26060802. 4460334.
  3. Uchino. A. Nomiyama. K. Takase. Y. Kudo. S. Anterior cerebral artery variations detected by MR angiography.. Neuroradiology. September 2006. 48. 9. 647–52. 16786350. 10.1007/s00234-006-0110-3. 8019565.
  4. Book: Ropper. A.. Samuels. M.. Klein. J.. Adams and Victor's Principles of Neurology. 2014. McGraw-Hill. 978-0071794794. 798. 10th.
  5. Book: Longo. D. Fauci. A. Kasper. D. Hauser. S. Jameson. J. Loscalzo. J. Harrison's Principles of Internal Medicine. 2012. McGraw-Hill. New York. 3286. 978-0071748896. 18th.