Immunoscintigraphy Explained

Immunoscintigraphy
Purpose:	detect cancer cells

Immunoscintigraphy is a nuclear medicine procedure used to find cancer cells in the body by injecting a radioactively labeled antibody, which binds predominantly to cancer cells and then scanning for concentrations of radioactive emissions.^{[1] [2]}

Clinical applications

Immunoscintigraphy is performed using a variety of radiopharmaceuticals, for a large range of purposes. Colorectal cancer is one of the most studied areas, with indium-111 or technetium-99m labelled epitopes of the carcinoembryonic antigen.^[3] The antibody capromab pendetide reacts with prostate membrane specific antigen (PMSA) and can be labelled with ¹¹¹In.^[4]

See also

• Indium-111 WBC scan
• Scintigraphy

Notes and References

1. Web site: Imaging Techniques for the Diagnosis of Ovarian Cancers: Immunoscintigraphy . 21 December 2004.
2. Web site: Immunoscintigraphy. NCI Dictionary of Cancer Terms. National Cancer Institute. 1 June 2017. en.
3. Book: Matzku. Siegfried. Stahel. Rolf A. Antibodies in Diagnosis and Therapy. 1999. CRC Press. 9789057023101. 143. en.
4. Fass. Leonard. Imaging and cancer: A review. Molecular Oncology. August 2008. 2. 2. 115–152. 10.1016/j.molonc.2008.04.001. 19383333. free. 5527766.