| Imidazoleacetate—phosphoribosyldiphosphate ligase | |
| Ec Number: | 6.3.4.8 |
| Cas Number: | 37318-65-3 |
| Go Code: | 0047483 |
In enzymology, an imidazoleacetate—phosphoribosyldiphosphate ligase is an enzyme that catalyzes a chemical reaction
ATP + imidazole-4-acetate + 5-phosphoribosyl diphosphate
\rightleftharpoons
The 3 substrates of this enzyme are ATP, imidazole-4-acetate, and 5-phosphoribosyl diphosphate, whereas its 4 products are ADP, phosphate, 1-(5-phosphoribosyl)imidazole-4-acetate, and diphosphate.
This enzyme belongs to the family of ligases, specifically those forming generic carbon-nitrogen bonds. The systematic name of this enzyme class is imidazoleacetate:5-phosphoribosyl-diphosphate ligase (ADP- and diphosphate-forming). This enzyme is also called 5-phosphoribosylimidazoleacetate synthetase. This enzyme participates in histidine metabolism.