Imidacloprid/moxidectin explained

Type:combo
Component1:Imidacloprid
Class1:Insecticide
Component2:Moxidectin
Class2:Anthelmintic
Tradename:Advantage Multi, Imoxi Topical Solution, Advocate
Dailymedid:Advantage multi
Routes Of Administration:Topical
Atc Prefix:None
Legal Ca:Rx-only
Legal Ca Comment:[1]
Legal Us:Rx-only
Legal Eu:Rx-only
Legal Eu Comment:[2]

Imidacloprid/moxidectin, sold under the brand names Advantage Multi for Dogs and Advantage Multi for Cats among others, is a medicine for dogs and cats to treat heartworm, fleas, sarcoptic mange, intestinal parasites and ear mites.[3] [4]

Medical uses

Imidacloprid/moxidectin is indicated for the prevention of heartworm disease caused by Dirofilaria immitis in dogs and cats. Imidacloprid/moxidectin kills adult fleas (Ctenocephalides felis) and is indicated for the treatment of flea infestations in dogs and cats.[5] [6] [7] [8]

Imidacloprid/moxidectin is indicated for the treatment of Dirofilaria immitis circulating microfilariae in heartworm-positive dogs. Imidacloprid/moxidectin is indicated for the treatment and control of sarcoptic mange caused by Sarcoptes scabiei var. canis. Imidacloprid/moxidectin is also indicated for the treatment and control of the specific intestinal parasites. It is also indicated for the treatment and control of intestinal roundworms (Toxocara canis and Toxascaris leonina), hookworms (Ancylostoma caninum and Uncinaria stenocephala), and whipworms (Trichuris vulpis).

In cats, imidacloprid/moxidectin is indicated for the treatment and control of ear mite (Otodectes cynotis) infestations and the following intestinal parasites: adult, immature adult, and fourth stage larvae in hookworms (Ancylostoma tubaeforme); and adult and fourth stage larvae in roundworms (Toxocara cati).[9] [10] [11]

Notes and References

  1. Web site: Health product highlights 2021: Annexes of products approved in 2021 . . 3 August 2022 . 25 March 2024.
  2. Web site: Advocate EPAR . European Medicines Agency (EMA) . 28 July 2009 . 29 January 2021.
  3. Web site: Advantage Multi for Dogs . U.S. Food and Drug Administration (FDA) . 28 May 2020.
  4. Web site: Advantage Multi for Cats . U.S. Food and Drug Administration (FDA) . 28 May 2020.
  5. Web site: Imoxi Topical Solution for Dogs FOIA Drug Summary . U.S. Food and Drug Administration (FDA) . 28 May 2020.
  6. Web site: Imoxi Topical Solution for Cats FOIA Drug Summary . U.S. Food and Drug Administration (FDA) . 28 May 2020.
  7. Web site: Imoxi Topical Solution for Dogs . U.S. Food and Drug Administration (FDA) . 28 May 2020.
  8. Web site: Advantage Multi for Dogs- imidacloprid moxidectin solution . DailyMed . 18 April 2018 . 29 May 2020.
  9. Web site: Advantage Multi for Cats- imidacloprid and moxidectin solution . DailyMed . 18 April 2018 . 28 May 2020.
  10. FDA Approves Generic Animal Drug for Parasite Protection in Cats . U.S. Food and Drug Administration (FDA) . 28 May 2020 . 28 May 2020.
  11. Web site: Imoxi Topical Solution for Cats . U.S. Food and Drug Administration (FDA) . 28 May 2020.

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