Hydroxynefazodone Explained

Hydroxynefazodone is a phenylpiperazine compound and a major metabolite of the antidepressant nefazodone.^{[1] [2]} It has similar biological activity and a similar elimination half-life (1.5 to 4 hours) to those of nefazodone, and may contribute significantly to its effects.

See also

• Serotonin antagonist and reuptake inhibitor

Notes and References

1. Book: Preskorn SH, Catterson ML . General Principles of Pharmacokinetics . Preskorn SH, Stanga CY, Feighner JP, Ross R . Antidepressants: Past, Present and Future . https://books.google.com/books?id=Ue3uCAAAQBAJ&pg=PA68. 6 December 2012. Springer Science & Business Media. 978-3-642-18500-7. 68–.
2. Davis R, Whittington R, Bryson HM . Nefazodone. A review of its pharmacology and clinical efficacy in the management of major depression . Drugs . 53 . 4 . 608–636 . April 1997 . 9098663 . 10.2165/00003495-199753040-00006 . 239077479 .