| hydroxymethylglutaryl-CoA hydrolase | |
| Ec Number: | 3.1.2.5 |
| Cas Number: | 9025-89-2 |
| Go Code: | 0047994 |
The enzyme hydroxymethylglutaryl-CoA hydrolase (EC 3.1.2.5) catalyzes the reaction
S-(2-hydroxyacyl)glutathione + H2O = glutathione + a 2-hydroxy carboxylate
This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name is S-(2-hydroxyacyl)glutathione hydrolase. Other names in common use include β-hydroxy-beta-methylglutaryl coenzyme A hydrolase, β-hydroxy-β-methylglutaryl coenzyme A deacylase, hydroxymethylglutaryl coenzyme A hydrolase, hydroxymethylglutaryl coenzyme A deacylase, and 3-hydroxy-3-methylglutaryl-CoA hydrolase.