Hydroxylysine kinase explained

hydroxylysine kinase
Ec Number:2.7.1.81
Cas Number:9073-58-9
Go Code:0047992

In enzymology, a hydroxylysine kinase is an enzyme that catalyzes the chemical reaction

GTP + 5-hydroxy-L-lysine

\rightleftharpoons

GDP + 5-phosphonooxy-L-lysine

Thus, the two substrates of this enzyme are GTP and 5-hydroxy-L-lysine, whereas its two products are GDP and 5-phosphonooxy-L-lysine.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is GTP:5-hydroxy-L-lysine O-phosphotransferase. Other names in common use include hydroxylysine kinase (phosphorylating), and guanosine triphosphate:5-hydroxy-L-lysine O-phosphotransferase. This enzyme participates in lysine degradation.

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