Hydroxylamine reductase (NADH) explained

hydroxylamine reductase (NADH)
Ec Number:	1.7.1.10
Cas Number:	9032-06-8
Go Code:	0050460

In enzymology, a hydroxylamine reductase (NADH) is an enzyme that catalyzes the chemical reaction.

NH₃ + NAD⁺ + H₂O

\rightleftharpoons hydroxylamine + NADH + H⁺

The 3 substrates of this enzyme are NH₃, NAD⁺, and H₂O, whereas its 3 products are hydroxylamine, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on other nitrogenous compounds as donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is ammonium:NAD+ oxidoreductase. Other names in common use include hydroxylamine reductase, ammonium dehydrogenase, NADH-hydroxylamine reductase, N-hydroxy amine reductase, hydroxylamine reductase (NADH2), and NADH2:hydroxylamine oxidoreductase. This enzyme participates in nitrogen metabolism.

References

• Bernheim ML . 1969 . The hydroxylamine reductase of mitochondria . Arch. Biochem. Biophys. . 134 . 408 - 13 . 4311180 . 10.1016/0003-9861(69)90300-2 . 2 .
• Bernheim ML, Hochstein P . 1968 . Reduction of hydroxylamine by rat liver mitochondria . Arch. Biochem. Biophys. . 124 . 436 - 42 . 4298499 . 10.1016/0003-9861(68)90349-4 . 1 .
• Wang R, Nicholas DJ . 1986 . Some properties of nitrite and hydroxylamine reductases from Derxia gummosa . . 25 . 2463 - 2469 . 10.1016/S0031-9422(00)84489-1 . 11 .