Hydrogenase (acceptor) explained

Hydrogenase (acceptor)
Ec Number:	1.12.99.6
Cas Number:	9027-05-8

In enzymology, a hydrogenase (acceptor) is an enzyme that catalyzes the chemical reaction

H₂ + A

\rightleftharpoons AH₂

Thus, the two substrates of this enzyme are H₂ and A, whereas its product is AH₂.

This enzyme belongs to the family of oxidoreductases, specifically those acting on hydrogen as donor with other acceptors. The systematic name of this enzyme class is hydrogen:acceptor oxidoreductase. Other names in common use include H2 producing hydrogenase[ambiguous], hydrogen-lyase[ambiguous], hydrogenlyase[ambiguous], uptake hydrogenase[ambiguous], and hydrogen:(acceptor) oxidoreductase.

References

• Shug AL, Wilson PW, Green DE, Mahler HR . 1954 . The role of molybdenum and flavin in hydrogenase . J. Am. Chem. Soc. . 76 . 3355 - 3356 . 10.1021/ja01641a090 . 12 .
• Adams MW, Mortenson LE, ((Chen J-S)) . 1981 . Hydrogenase . Biochim. Biophys. Acta . 594 . 105 - 176 . 10.1016/0304-4173(80)90007-5 .
• Vignais PM, Billoud B, Meyer J . 2001 . Classification and phylogeny of hydrogenases . FEMS Microbiol. Rev. . 25 . 455 - 501 . 11524134 . 4 . 10.1111/j.1574-6976.2001.tb00587.x. free .