A hyaline substance is one with a glassy appearance. The word is derived from Greek, Modern (1453-);: ὑάλινος|translit=hyálinos|lit=transparent, and Greek, Modern (1453-);: ὕαλος|translit=hýalos|lit=crystal, glass|label=none.[1] [2]
Hyaline cartilage is named after its glassy appearance on fresh gross pathology.[3] On light microscopy of H&E stained slides, the extracellular matrix of hyaline cartilage looks homogeneously pink, and the term "hyaline" is used to describe similarly homogeneously pink material besides the cartilage. Hyaline material is usually acellular and proteinaceous. For example, arterial hyaline is seen in aging, high blood pressure, diabetes mellitus and in association with some drugs (e.g. calcineurin inhibitors). It is bright pink with PAS staining.
In ichthyology and entomology, hyaline denotes a colorless, transparent substance, such as unpigmented fins of fishes or clear insect wings.[4]
In botany, hyaline refers to thin and translucent plant parts, such as the margins of some sepals, bracts and leaves.