| Homoglutathione synthase | |
| Ec Number: | 6.3.2.23 |
| Cas Number: | 113875-72-2 |
| Go Code: | 0047983 |
In enzymology, a homoglutathione synthase is an enzyme that catalyzes the chemical reaction
ATP + γ-L-glutamyl-L-cysteine + β-alanine
\rightleftharpoons
The 3 substrates of this enzyme are ATP, gamma-L-glutamyl-L-cysteine, and beta-alanine, whereas its 3 products are ADP, phosphate, and gamma-L-glutamyl-L-cysteinyl-beta-alanine.
This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds as acid-D-amino-acid ligases (peptide synthases). The systematic name of this enzyme class is gamma-L-glutamyl-L-cysteine:beta-alanine ligase (ADP-forming). Other names in common use include homoglutathione synthetase, and beta-alanine specific hGSH synthetase.