Homing (hematopoietic) explained

Homing is the phenomenon whereby cells migrate to the organ of their origin. By homing, transplanted hematopoietic cells are able to travel to and engraft (establish residence) in the bone marrow. Various chemokines[1] and receptors[2] are involved in the homing of hematopoietic stem cells.[3]

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Notes and References

  1. Book: Cyster, JG. Ngo, VN . Ekland, EH . Gunn, MD . Sedgwick, JD . Ansel, KM . Chemokines and B-cell homing to follicles. 1999. 246. 87–92; discussion 93. 10396043. 10.1007/978-3-642-60162-0_11. Current Topics in Microbiology and Immunology. 978-3-642-64283-8.
  2. Lopez-Giral. S.. Chemokine receptors that mediate B cell homing to secondary lymphoid tissues are highly expressed in B cell chronic lymphocytic leukemia and non-Hodgkin lymphomas with widespread nodular dissemination. Journal of Leukocyte Biology. 23 April 2004. 76. 2. 462–471. 10.1189/jlb.1203652. 15155773. Quintana. NE. Cabrerizo. M. Alfonso-Pérez. M. Sala-Valdés. M. De Soria. VG. Fernández-Rañada. JM. Fernández-Ruiz. E. Muñoz. C. free.
  3. Yusuf. Rushdia Z.. Scadden, David T.. Homing of Hematopoietic Cells to the Bone Marrow. Journal of Visualized Experiments. 17 March 2009. 25. e1104. 10.3791/1104. 23 December 2012. 2762899. 19295497.
  4. von Andrian . Ulrich H. . Mempel, Thorsten R. . Homing and cellular traffic in lymph nodes . Nature Reviews Immunology . 1 November 2003 . 3 . 11 . 867–878 . 10.1038/nri1222 . https://web.archive.org/web/20100729034524/http://labs.idi.harvard.edu/vonandrian/Pages/mempelvonandriannri.pdf . dead . 29 July 2010 . 23 December 2012 . 14668803 . 5199142 .

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