Hispidin Explained

Hispidin is a natural substance. It can also be synthesized.^[1]

Hispidin 4-O-β-D-glucopyranoside can be found in Pteris ensiformis^[2] whereas hispidin derivatives, such as phellibaumins, can be found in the edible mushroom Inonotus xeranticus^[3] or Phellinus.^{[4] [5]} Hispidin is a precursor of fungal luciferin, a compound responsible for light emission by luminous mushrooms.

See also

• Davallialactone
• Phellibaumin

Notes and References

1. 9088624 . 10.1023/A:1007321227010 . 1997 . Gonindard . C. . Bergonz i. C. . Denier . C. . Sergheraert . C. . Klaebe . A. . Chavant . L. . Hollande . E. . Cell Biology and Toxicology . 13 . 3 . 141–53 . Synthetic hispidin, a PKC inhibitor, is more cytotoxic toward cancer cells than normal cells in vitro. 755744 .
2. 10.1016/j.foodchem.2007.03.055 . Identification of phenolic antioxidants from Sword Brake fern (Pteris ensiformis Burm.) . Food Chemistry . 105 . 48–56 . 2007 . Chen . Y. . Chang . F. . Lin . Y. . Wang . L. . Chen . J. . Wu . Y. . Wu . M. .
3. 10.1021/np050453n. 16499338. Hispidin Derivatives from the Mushroom Inonotusxeranticusand Their Antioxidant Activity. Journal of Natural Products. 69. 2. 299–301. 2006. Lee. In-Kyoung. Seok. Soon-Ja. Kim. Wan-Kyu. Yun. Bong-Sik.
4. 10.1016/j.bmc.2007.03.039 . Highly oxygenated and unsaturated metabolites providing a diversity of hispidin class antioxidants in the medicinal mushrooms Inonotus and Phellinus . 2007 . Lee . In-Kyoung . Yun . Bong-Sik . Bioorganic & Medicinal Chemistry . 15 . 10 . 3309–14 . 17387019.
5. 10.1248/bpb.31.1968 . Protein glycation inhibitors from the fruiting body of Phellinus linteus . Biological & Pharmaceutical Bulletin . 31 . 10 . 1968–72 . October 2008 . 18827365 . Lee . Yeon Sil . Kang . Young-Hee . Jung . Ju-Young . Lee . Sanghyun . Ohuchi . Kazuo . Shin . Kuk Hyun . Kang . Il-Jun . Park . Jung Han Yoon . Shin . Hyun-Kyung. Lim . Soon Sung . 8 . free .