Hereditary benign intraepithelial dyskeratosis explained

Hereditary benign intraepithelial dyskeratosis is a rare^[1] autosomal dominant disease of the conjunctiva and the oral mucosa caused by a duplication of chromosome 4q35.^[2] In the mouth it appears similar to white sponge nevus, with painless, diffuse, folded and spongy white plaques. In the eye it appears as gelatinous plaques on bulbar perilimbal conjunctiva.

Notes and References

1. Bui. T. Young. JW. Frausto. RF. Markello. TC. Glasgow. BJ. Aldave. AJ. Hereditary Benign Intraepithelial Dyskeratosis: Report of a Case and Re-examination of the Evidence for Locus Heterogeneity.. Ophthalmic Genetics. 20 February 2014. 37. 1. 24555743. 4139474. 10.3109/13816810.2014.889169. 76–80.
2. Book: Woo SB. Oral Pathology: A Comprehensive Atlas and Text. 2012. Elsevier Health Sciences. 978-1-4377-2226-0. 9.