Heparan sulfate 6-O-sulfotransferase explained

Heparan sulfate 6-sulfotransferases catalyses the transfer of sulfate from adenosine 3'-phosphate, 5'-phosphosulfate to the 6th position of the N-sulfoglucosamine residue in heparan sulfate.^[1]

Human proteins containing this domain

• HS6ST1
• HS6ST2
• HS6ST3

Notes and References

1. Matsuda Y, Kuroiwa A, Tanaka M, Habuchi H, Miyake G, Nogami K, Kusche-gullberg M, Habuchi O, Kimata K . Biosynthesis of heparan sulphate with diverse structures and functions: two alternatively spliced forms of human heparan sulphate 6-O-sulphotransferase-2 having different expression patterns and properties . Biochem. J. . 371 . Pt 1. 131–142 . 2003 . 12492399 . 10.1042/BJ20021259 . 1223259.