Hemifacial hypertrophy explained

Synonyms:	Friedreich's disease

Hemifacial hypertrophy (also termed facial hemihypertrophy, facial hemihyperplasia,^[1] or Friedreich's disease)^[2] abbreviated as (HFH) is rare congenital disease characterized by unilateral enlargement of the head and teeth.^{[3] [4]} It is classified as true HFH (THFH) with unilateral enlargement of the viscerocranium, and partial HFH (PHFH) in which not all structures are enlarged. Hemifacial hypertrophy can cause a wide spectrum of defects or may involve only muscle or bone.^[4] it is usually treated surgically.^[5] It is believed to be a minor form of hemihypertrophy.^[6]

Notes and References

1. Book: Rajendran A. Sundaram S. Shafer's Textbook of Oral Pathology. 7th. 10 February 2014. Elsevier Health Sciences APAC. 978-81-312-3800-4. 13.
2. Book: Ghom AG. Ghom SA. Textbook of Oral Medicine. 30 September 2014. JP Medical Ltd. 978-93-5152-303-1. 125.
3. Lee S, Sze R, Murakami C, Gruss J, Cunningham M . Hemifacial myohyperplasia: description of a new syndrome . . 103 . 4 . 326–33 . November 2001 . 11746014. 10.1002/1096-8628(20011101)103:4<326::AID-AJMG1578>3.0.CO;2-Z .
4. Islam MN, Bhattacharyya I, Ojha J, Bober K, Cohen DM, Green JG . Comparison between true and partial hemifacial hypertrophy . . 104 . 4 . 501–9 . October 2007 . 17448705 . 10.1016/j.tripleo.2006.11.053 .
5. Pollock RA, Newman MH, Burdi AR, Condit DP . Congenital hemifacial hyperplasia: an embryologic hypothesis and case report . . 22 . 3 . 173–84 . July 1985 . 3860311 .
6. Urban PP, Bruening R, Roland B . 1982190 . Congenital isolated hemifacial hyperplasia . J. Neurol. . 256 . 9 . 1566–9 . September 2009 . 19424770 . 10.1007/s00415-009-5148-9 .