Hairy RNA localisation element (HLE) explained
| Hairy RNA localisation element (HLE) |
| Symbol: | HLE |
| Rfam: | RF00437 |
| Rna Type: | Cis-reg |
| Tax Domain: | Eukaryota |
The hairy localisation element (HLE) is an RNA element found in the 3' UTR of the hairy gene. HLE contains two stem-loops. HLE is essential for the mediation of apical localisation and the two stem-loop structures act to allow the recognition of hairy mRNA by the localisation machinery.[1] HLE is found in Drosophila species.
Notes and References
- Bullock SL, Zicha D, Ish-Horowicz D . The Drosophila hairy RNA localization signal modulates the kinetics of cytoplasmic mRNA transport . The EMBO Journal . 22 . 10 . 2484–2494 . May 2003 . 12743042 . 155988 . 10.1093/emboj/cdg230 .
