Guanosine-diphosphatase explained

guanosine-diphosphatase
Ec Number:	3.6.1.42
Cas Number:	98037-56-0
Go Code:	0004382

In enzymology, a guanosine-diphosphatase is an enzyme that catalyzes the chemical reaction

GDP + H₂O

\rightleftharpoons GMP + phosphate

Thus, the two substrates of this enzyme are GDP and H₂O, whereas its two products are GMP and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is GDP phosphohydrolase. This enzyme is also called GDPase.

References

• Raychaudhuri P, Ghosh S, Maitra U . 1985 . Purification and characterization of a guanosine diphosphatase activity from calf liver microsomal salt wash proteins . J. Biol. Chem. . 260 . 8306 - 11 . 2989286 . 14 .