GPR endopeptidase explained

Gpr endopeptidase
Ec Number:3.4.24.78
Cas Number:75718-32-0

GPR endopeptidase (germination proteinase) is an enzyme.[1] This enzyme catalyses the following chemical reaction:

Endopeptidase action with P4 Glu or Asp, P1 preferably Glu > Asp, P1' hydrophobic and P2' Ala

This enzyme participates in spore germination in Bacillus megaterium.

Notes and References

  1. Ponnuraj K, Rowland S, Nessi C, Setlow P, Jedrzejas MJ . Crystal structure of a novel germination protease from spores of Bacillus megaterium: structural arrangement and zymogen activation . Journal of Molecular Biology . 300 . 1 . 1–10 . June 2000 . 10864493 . 10.1006/jmbi.2000.3849 .