| Gmina Łyse | |
| Other Name: | Łyse Commune |
| Settlement Type: | Gmina |
| Total Type: | Total |
| Pushpin Map: | Poland |
| Pushpin Label Position: | bottom |
| Subdivision Type: | Country |
| Subdivision Type1: | Voivodeship |
| Subdivision Name1: | Masovian |
| Subdivision Type2: | County |
| Subdivision Name2: | Ostrołęka County |
| Coor Pinpoint: | Łyse |
| Coordinates: | 53.3642°N 21.565°W |
| Area Total Km2: | 246.45 |
| Population Total: | 8394 |
| Population As Of: | 2011[1] |
| Population Density Km2: | auto |
| Seat: | Łyse |
| Website: | http://www.gminalyse.pl/ |
Gmina Łyse is a rural gmina (administrative district) in Ostrołęka County, Masovian Voivodeship, in east-central Poland. Its seat is the village of Łyse, which lies approximately 31 kilometres (19 mi) north of Ostrołęka and 132 km (82 mi) north-east of Warsaw.
The gmina covers an area of 246.45km2, and as of 2006 its total population is 7,908 (8,394 in 2011).
Gmina Łyse contains the villages and settlements of Antonia, Baba, Dawia, Dęby, Dudy Puszczańskie, Grądzkie, Klenkor, Łączki, Lipniki, Łyse, Piątkowizna, Plewki, Pupkowizna, Serafin, Szafranki, Tartak, Tyczek, Warmiak, Wejdo, Wyżega, Zalas and Złota Góra.
Gmina Łyse is bordered by the gminas of Kadzidło, Myszyniec, Pisz, Rozogi, Turośl and Zbójna.