glyoxylate reductase (NADP) | |
Ec Number: | 1.1.1.79 |
Cas Number: | 37250-17-2 |
Go Code: | 0030267 |
In enzymology, a glyoxylate reductase (NADP+) is an enzyme that catalyzes the chemical reaction
glycolate + NADP+
\rightleftharpoons
Thus, the two substrates of this enzyme are glycolate and NADP+, whereas its 3 products are glyoxylate, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is glycolate:NADP+ oxidoreductase. Other names in common use include NADPH-glyoxylate reductase, and glyoxylate reductase (NADP+). This enzyme participates in pyruvate metabolism and glyoxylate and dicarboxylate metabolism.
As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes,, and .