Glycosulfatase Explained

glycosulfatase
Ec Number:	3.1.6.3
Cas Number:	9025-61-0
Go Code:	0047966

The enzyme glycosulfatase (EC 3.1.6.3)^{[1] [2] [3]} catalyzes the reaction

D-glucose 6-sulfate + H₂O

\rightleftharpoons D-glucose + sulfate

This enzyme belongs to the family of hydrolases, specifically those acting on sulfuric ester bonds. The systematic name of this enzyme class is sugar-sulfate sulfohydrolase. This enzyme is also called glucosulfatase. This enzyme participates in glycolysis and gluconeogenesis.

Notes and References

1. • Dodgson KS . 1961 . Glycosulphatase: observations on the activity of partially purified preparations towards the sulphate esters of certain monosaccharides and steroids . Biochem. J. . 78 . 324 - 333 . 16748876 . 2 . 1205270. 10.1042/bj0780324 .
2. Egami F . Takahaski N . 1955 . Syntheses of adenosinesulfuric acids . Bull. Chem. Soc. Jpn. . 28 . 666 - 668 . 10.1246/bcsj.28.666 . 9 . free .
3. Roy, AB . 1960 . The synthesis and hydrolysis of sulfate esters . Adv. Enzymol. Relat. Subj. Biochem. . 22 . 205 - 235 .