Glycosphingolipid deacylase explained

Glycosphingolipid deacylase
Ec Number:	3.5.1.69
Cas Number:	122544-53-0

In enzymology, a glycosphingolipid deacylase is an enzyme that catalyzes a chemical reaction that cleaves gangliosides and neutral glycosphingolipids, releasing fatty acids to form the lyso-derivatives.

This enzyme belongs to the family of hydrolases, specifically those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is glycosphingolipid amidohydrolase. This enzyme is also called glycosphingolipid ceramide deacylase.

References

• Hirabayashi Y, Kimura M, Matsumoto M, Yamamoto K, Kadowaki S, Tochikura T . A novel glycosphingolipid hydrolyzing enzyme, glycosphingolipid ceramide deacylase, which cleaves the linkage between the fatty acid and sphingosine base in glycosphingolipids . Journal of Biochemistry . 103 . 1 . 1–4 . January 1988 . 3360750 .