| glycolaldehyde dehydrogenase | |
| Ec Number: | 1.2.1.21 |
| Cas Number: | 37250-89-8 |
| Go Code: | 0050569 |
In enzymology, a glycolaldehyde dehydrogenase is an enzyme that catalyzes the chemical reaction
glycolaldehyde + NAD+ + H2O
\rightleftharpoons
The 3 substrates of this enzyme are glycolaldehyde, NAD+, and H2O, whereas its 3 products are glycolate, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is glycolaldehyde:NAD+ oxidoreductase. This enzyme is also called glycol aldehyde dehydrogenase. This enzyme participates in glyoxylate and dicarboxylate metabolism.
As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes,, and .