| glycine transaminase | |
| Ec Number: | 2.6.1.4 |
| Cas Number: | 9032-99-9 |
| Go Code: | 0047958 |
In enzymology, a glycine transaminase is an enzyme that catalyzes the chemical reaction
glycine + 2-oxoglutarate
\rightleftharpoons
Thus, the two substrates of this enzyme are glycine and 2-oxoglutarate, whereas its two products are glyoxylate and L-glutamate.
This reactions strongly favours synthesis of glycine.[1] This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is glycine:2-oxoglutarate aminotransferase. Other names in common use include glutamic-glyoxylic transaminase, glycine aminotransferase, glyoxylate-glutamic transaminase, L-glutamate:glyoxylate aminotransferase, and glyoxylate-glutamate aminotransferase. This enzyme participates in glycine, serine and threonine metabolism. It employs one cofactor, pyridoxal phosphate.