Glycine N-phenylacetyltransferase explained

Glycine N-phenylacetyltransferase
Ec Number:2.3.1.192

Glycine N-phenylacetyltransferase (arylacetyl-CoA N-acyltransferase, arylacetyltransferase, GAT (gene)) is an enzyme with systematic name phenylacetyl-CoA:glycine N-phenylacetyltransferase.[1] [2] [3] This enzyme catalyses the following chemical reaction

\rightleftharpoons

CoA + phenylacetylglycine

This enzyme was purified from bovine liver mitochondria.

Notes and References

  1. Nandi DL, Lucas SV, Webster LT . Benzoyl-coenzyme A:glycine N-acyltransferase and phenylacetyl-coenzyme A:glycine N-acyltransferase from bovine liver mitochondria. Purification and characterization . The Journal of Biological Chemistry . 254 . 15 . 7230–7 . August 1979 . 457678 .
  2. Kelley M, Vessey DA . The effects of ions on the conjugation of xenobiotics by the aralkyl-CoA and arylacetyl-CoA N-acyltransferases from bovine liver mitochondria . Journal of Biochemical Toxicology . 5 . 2 . 125–35 . 1990 . 2283662 . 10.1002/jbt.2570050208 .
  3. Vessey DA, Lau E . Determination of the sequence of the arylacetyl acyl-CoA:amino acid N-acyltransferase from bovine liver mitochondria and its homology to the aralkyl acyl-CoA:amino acid N-acyltransferase . Journal of Biochemical and Molecular Toxicology . 12 . 5 . 275–9 . 1998 . 9664233 . 10.1002/(sici)1099-0461(1998)12:5<275::aid-jbt3>3.0.co;2-i .