Glycerol dehydratase explained
| glycerol dehydratase |
| Ec Number: | 4.2.1.30 |
| Cas Number: | 9077-68-3 |
| Go Code: | 0046405 |
In enzymology, a glycerol dehydratase catalyzes the chemical reaction
glycerol
3-hydroxypropanal + H
2O
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is glycerol hydro-lyase (3-hydroxypropanol-forming). Other names in common use include glycerol dehydrase, and glycerol hydro-lyase. This enzyme participates in glycerolipid metabolism. It employs one cofactor, cobalamin.
Structural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes and .
References
- Forage RG, Foster MA . 1982 . Glycerol fermentation in Klebsiella pneumoniae: functions of the coenzyme B12-dependent glycerol and diol dehydratases . J. Bacteriol. . 149 . 413 - 9 . 7035429 . 2 . 10.1128/JB.149.2.413-419.1982 . 216523 .
- Schneider Z, Larsen EG, Jacobson G, Johnson BC, Pawelkiewicz J . 1970 . Purification and properties of glycerol dehydrase . J. Biol. Chem. . 245 . 3388 - 96 . 4989992 . 13 . 10.1016/S0021-9258(18)63008-X . free .
- Schneider Z, Pawelkiewicz J . 1966 . The properties of glycerol dehydratase isolated from Aerobacter aerogenes, and the properties of the apoenzyme subunits . Acta Biochim. Pol. . 13 . 311 - 28 . 5962440 . 4 .
- SMILEY KL, SOBOLOV M . 1962 . A cobamide-requiring glycerol dehydrase from an acrolein-forming Lactobacillus . Arch. Biochem. Biophys. . 97 . 538 - 43 . 14039344 . 10.1016/0003-9861(62)90118-2 . 3 .
