Glycerol-3-phosphate 2-O-acyltransferase explained

Glycerol-3-phosphate 2-O-acyltransferase
Ec Number:	2.3.1.198

Glycerol-3-phosphate 2-O-acyltransferase (sn-2-glycerol-3-phosphate O-acyltransferase, glycerol-3-phosphate O-acyltransferase) is an enzyme with systematic name acyl-CoA:sn-glycerol 3-phosphate 2-O-acyltransferase.^[1] This enzyme catalyses the following chemical reaction

acyl-CoA + sn-glycerol 3-phosphate

\rightleftharpoons CoA + a 2-acyl-sn-glycerol 3-phosphate

This membrane-associated enzyme is required for suberin or cutin synthesis in plants.

Notes and References

1. Yang W, Pollard M, Li-Beisson Y, Beisson F, Feig M, Ohlrogge J . A distinct type of glycerol-3-phosphate acyltransferase with sn-2 preference and phosphatase activity producing 2-monoacylglycerol . Proceedings of the National Academy of Sciences of the United States of America . 107 . 26 . 12040–5 . June 2010 . 20551224 . 2900678 . 10.1073/pnas.0914149107 . 2010PNAS..10712040Y . free .