| glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | |
| Ec Number: | 1.2.1.12 |
| Cas Number: | 9001-50-7 |
| Go Code: | 0004365 |
| Width: | 270 |
In enzymology, a glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) is an enzyme that catalyzes the chemical reaction
D-glyceraldehyde 3-phosphate + phosphate + NAD+
\rightleftharpoons
The 3 substrates of this enzyme are D-glyceraldehyde 3-phosphate, phosphate, and NAD+, whereas its 3 products are 3-phospho-D-glyceroyl phosphate, NADH, and H+. This enzyme participates in glycolysis / gluconeogenesis.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-glyceraldehyde-3-phosphate:NAD+ oxidoreductase (phosphorylating). Other names in common use include triosephosphate dehydrogenase, dehydrogenase, glyceraldehyde phosphate, phosphoglyceraldehyde dehydrogenase, 3-phosphoglyceraldehyde dehydrogenase, NAD+-dependent glyceraldehyde phosphate dehydrogenase, glyceraldehyde phosphate dehydrogenase (NAD+), glyceraldehyde-3-phosphate dehydrogenase (NAD+), NADH-glyceraldehyde phosphate dehydrogenase, and glyceraldehyde-3-P-dehydrogenase.