| glutathione-CoA—glutathione transhydrogenase | |
| Ec Number: | 1.8.4.3 |
| Cas Number: | 37256-48-7 |
| Go Code: | 0047140 |
In enzymology, a glutathione—CoA-glutathione transhydrogenase is an enzyme that catalyzes the chemical reaction
CoA + glutathione disulfide
\rightleftharpoons
Thus, the two substrates of this enzyme are CoA and glutathione disulfide, whereas its two products are CoA-glutathione and glutathione.
This enzyme belongs to the family of oxidoreductases, specifically those acting on a sulfur group of donors with a disulfide as acceptor. The systematic name of this enzyme class is CoA:glutathione-disulfide oxidoreductase. Other names in common use include glutathione-coenzyme A glutathione disulfide transhydrogenase, glutathione-coenzyme A glutathione disulfide transhydrogenase, glutathione coenzyme A-glutathione transhydrogenase, glutathione:coenzyme A-glutathione transhydrogenase, coenzyme A:oxidized-glutathione oxidoreductase, and coenzyme A:glutathione-disulfide oxidoreductase. This enzyme participates in cysteine metabolism and glutathione metabolism.