Glutamate dehydrogenase (NAD(P)+) explained

Glutamate dehydrogenase (NAD(P)+)
Ec Number:	1.4.1.3
Cas Number:	2604152
Width:	270

Glutamate dehydrogenase (NAD(P)+) (glutamic dehydrogenase, glutamate dehydrogenase [NAD(P)+]) is an enzyme with systematic name L-glutamate:NAD(P)+ oxidoreductase (deaminating).^{[1] [2] [3]} This enzyme catalyses the following chemical reaction

L-glutamate + H2O + NAD(P)+

\rightleftharpoons 2-oxoglutarate + NH4+ + NAD(P)H + H+

Notes and References

1. Olson JA, Anfinsen CB . The crystallization and characterization of L-glutamic acid dehydrogenase . The Journal of Biological Chemistry . 197 . 1 . 67–79 . May 1952 . 12981035 .
2. Book: Glutamate dehydrogenases . The Enzymes . Smith, E.L. . Austen, B.M. . Blumenthal, K.M. . Nyc, J.F. . 1975 . 11 . 293–367 . Boyer, P.D. . 3rd . Academic Press . New York .
3. Strecker HJ . Glutamic dehydrogenase . Archives of Biochemistry and Biophysics . 46 . 1 . 128–40 . September 1953 . 13092953 . 10.1016/0003-9861(53)90176-3 .