| glucuronolactone reductase | |
| Ec Number: | 1.1.1.20 |
| Cas Number: | 9028-30-2 |
| Go Code: | 0047941 |
In enzymology, a glucuronolactone reductase is an enzyme that catalyzes the chemical reaction
L-gulono-1,4-lactone + NADP+
\rightleftharpoons
Thus, the two substrates of this enzyme are L-gulono-1,4-lactone and NADP+, whereas its 3 products are D-glucurono-3,6-lactone, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-gulono-1,4-lactone:NADP+ 1-oxidoreductase. Other names in common use include GRase, and gulonolactone dehydrogenase. This enzyme participates in ascorbate and aldarate metabolism.