Glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase explained

glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase
Ec Number:	3.1.4.51
Cas Number:	123940-44-3
Go Code:	0047399

The enzyme glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase (EC 3.1.4.51) catalyzes the reaction

6-(D-glucose-1-phospho)-D-mannosylglycoprotein + H₂O

\rightleftharpoons α-D-glucose 1-phosphate + D-mannosylglycoprotein

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name of this enzyme class is 6-(D-glucose-1-phospho)-D-mannosylglycoprotein glucose-1-phosphohydrolase. This enzyme is also called α-glucose-1-phosphate phosphodiesterase.

References

• Srisomsap C, Richardson KL, Jay JC, Marchase RB . 1989 . An α-glucose-1-phosphate phosphodiesterase is present in rat liver cytosol . J. Biol. Chem. . 264 . 20540 - 6 . 2555363 . 34 .