Glucose-1-phosphatase explained

glucose-1-phosphatase
Ec Number:	3.1.3.10
Cas Number:	9001-38-1
Go Code:	0008877

The enzyme glucose-1-phosphatase (EC 3.1.3.10) catalyzes the reaction

α-D-glucose 1-phosphate + H₂O

\rightleftharpoons D-glucose + phosphate

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name is α-D-glucose-1-phosphate phosphohydrolase. This enzyme participates in glycolysis and gluconeogenesis.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code .

References

• Faulkner P . A hexose-1-phosphatase in silkworm blood . The Biochemical Journal . 60 . 4 . 590–6 . August 1955 . 10.1042/bj0600590 . 13249953 . 1216157 .
• Turner DH, Turner JF . The hydrolysis of glucose monophosphates by a phosphatase preparation from pea seeds . The Biochemical Journal . 74 . 3 . 486–91 . March 1960 . 10.1042/bj0740486 . 13839934 . 1204246 .