| glucosamine-6-phosphate deaminase | |
| Ec Number: | 3.5.99.6 |
| Cas Number: | 9013-10-9 |
| Go Code: | 0004342 |
| Width: | 270 |
In enzymology, a glucosamine-6-phosphate deaminase is an enzyme that catalyzes the chemical reaction
D-glucosamine 6-phosphate + H2O
\rightleftharpoons
Thus, the two substrates of this enzyme are glucosamine 6-phosphate and H2O, whereas its two products are fructose 6-phosphate and NH3.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in compounds that have not been otherwise categorized within EC number 3.5. The systematic name of this enzyme class is 2-amino-2-deoxy-D-glucose-6-phosphate aminohydrolase (ketol isomerizing). Other names in common use include glucosaminephosphate isomerase, glucosamine-6-phosphate isomerase, phosphoglucosaminisomerase, glucosamine phosphate deaminase, aminodeoxyglucosephosphate isomerase, and phosphoglucosamine isomerase. This enzyme participates in aminosugars metabolism. This enzyme has at least one effector, N-Acetyl-D-glucosamine 6-phosphate.
As of late 2007, 5 structures have been solved for this class of enzymes, with PDB accession codes,,,, and .